Trying To Reverse Grey Hair

Posted on May 10, 2012 by Hair Loss Hair

Without a doubt facial wrinkles and hair loss are sure signs were getting older but for some grey hair is more obviously than anything else. Trying to reverse grey hair or at least hiding it has been in the works since the times of ancient Egypt man who had struggled to disguise the problem.

Methods Of Trying To Reverse Grey Hair

One of the earliest methods used was “Henna” which is a flowering plant used since antiquity to dye hair, skin, fingernails and even leather and wool which gives a reddish appearance.

Coal tar was another popular substances that was relied upon to color grey hair also.

Facts is hair color is the pigmentation of hair follicles due to two types of melanin, these are eumelanin and pheomelanin. Typically the way it works is the more melanin present, the darker your hair will be and on the flip side the less melanin there is will causes hair to become lighter. Melanin, a type of protein can be denatured by various chemicals, including bleach. This is how dark hair is transformed into blonde hair.

Melanin And How To Reverse Grey Hair

As we’ve noted, two types of pigment give hair its color: eumelanin and pheomelanin. Pheomelanin colors hair red. Eumelanin, which has two subtypes of black or brown, determines the darkness of the hair color. A low concentration of brown eumelanin results in blond hair, whereas a higher concentration of brown eumelanin will color the hair brown.

High amounts of black eumelanin result in black hair, while low concentrations yield gray hair. All humans have some pheomelanin in their hair.

Understanding How To Reverse Grey Hair

Pheomelanin is more chemically stable than black eumelanin, but less chemically stable than brown eumelanin, so it breaks down more slowly when oxidized. This is why bleach causes darker hair to go through a reddish phase during the artificial coloring process. As the pheomelanin continues to break down, hair gradually becomes orange, then yellow, and finally white.

Levels of melanin can vary over time causing a person’s hair color to change, and it is possible to have hair follicles of more than one color. Gray or white hair still today called “salt and pepper” when it is ‘peppered’ throughout dark hair, is not caused by a true gray or white pigment, but is due to a lack of pigmentation or melanin.

At the present time there is no medical (i.e. permanent) means to restore melanin pigment lost due to aging to reverse grey hair. As with efforts to reverse pattern hair loss, the basis for restoring hair pigment comes down to molecular medicine. Using a gene modulation approach, the goal would be to ‘turn on’ melanocyte producing genes so that the pigment producing cells could once again populate the hair with it’s natural color.

The development of a stem cell-based technique would yield actual melanocytes capable of being replaced in the hair follicle so that they could resume their production of eumelanin and pheomelanin. In either theoretical technique the potential to modulate melanocyte expression is likely. In plain English, this means that a person could choose whatever shade of hair he or she wishes perhaps even sades of purple or green not found in nature.

If you want to reverse grey hair then see what Greyban can do for you.

Author: New Hair Genesis

Posted in Uncategorized | Tagged aging, dark hair, follicle, gray hair, grey hair, hair color, hair follicles, hair genesis, hairgenesis, pattern hair loss, Reverse Grey Hair | Leave a comment

Listen to This About Curing Baldness

Posted on May 5, 2012 by Hair Loss Hair

Curing baldness is in the news and I thought I would share this interesting piece of information with those who like me were thinking there was no hope for curing baldness.

Last week, ABC News reported that ”Japanese scientists have successfully regenerated hair on a bald mouse, bringing hope to more than 50 million Americans suffering from hair loss.” by curing baldness. The story went on to say “In a breakthrough study, researchers at the Tokyo University of Science extracted stem cells from hair follicles in normal mice, and implanted them into the skin of the bald animal. Most grew hair back within two to five weeks, and underwent normal growth cycles, meaning the strands grew back even after they were pulled out. They established connections to muscles and nerves underneath the skin, just like natural hair.”

Drawing a correlation between the Japanese mouse study and human hair loss, the ABC News article concluded with the cautious words “None of the studies have led to cures for hair loss in humans.” At least no yet. Still, despite the careful disclaimer, most interested readers will likely infer that the Japanese study has broken new ground in the effort to curing baldness.

The facts though speak to a somewhat different conclusion. To begin, it must be noted that several years ago workers at Columbia University and elsewhere managed to grow hair on the hairless mouse model. So despite the recent Japanese announcement, there is not really anything new here. In fact, it was Dr. Angela Christiano working with colleagues at Columbia University in the 1990′s who first drew the genetic link between this mouse and a rare inherited form of human hair loss, known as ‘congenital atrichia’. Both the ‘hairless mouse’ and its human counterpart suffer from a zinc finger transcription gene defect which, among other consequences, triggers apoptosis (complete destruction) of the proliferative hair growing elements in affected organisms. Moreover, the hairless mouse model is a very poor analog for the most common form of hair loss affecting humans.

Curing Baldness

Though both congenital atrichia and AGA affect humans, it is equally important to understand that congenital atrichia shares absolutely no genetic homology with common pattern hair loss. There are perhaps twenty or thirty known cases of congenital atrichia worldwide. Common pattern hair loss, also known as androgenetic alopecia (AGA) affects more than tens of millions people worldwide.

Unfortunately, the hairless mouse offers no biochemical or genetic assistance in curing pattern hair loss. Actually, there is no animal model for AGA. This fact alone has significantly slowed the progress toward developing a true cure. Moreover, unlike congenital atrichia, AGA is not a monogenic (single gene) disorder, but a complex trait disease. This means that there are numerous factors, both genetic and eipgenetic which influence the onset and progression of AGA. For instance it is thought that as many as twenty genes may govern hair growth, hair cycling and hair loss. While some genes probably play a much greater role than others, the details are still being worked out. In our lab, we have uncovered several noteworthy genetic clues which point toward the role micro-inflammation plays in AGA.

Inflammatory Process

Undoubtedly, with time, additional important contributing factors will be elucidated, each representing a touchstone that will need to be addressed as we move away from treatment and toward a genuine cure. This effort will constitute a mosaic of contribution from investigators working in dedicated facilities worldwide. However, despite recent press attention given to the laudable Japanese effort, the possibility that tomorrow news headlines will announce “Hair Loss Cure Discovered” remains vanishingly remote.

Once the hair follicle dies there is no bring back dead cells. The trick is the get them before they die by stopping hair follicle miniaturization. This can be done with natural hair loss products. The trick to curing baldness is to prevent it.

Posted in Uncategorized | Tagged androgenetic alopecia, bald, columbia university, curing baldness, grow hair, hair follicles, hair growth, hair loss products, hairgenesis, miniaturization, pattern hair loss, stem cells | Leave a comment

News About Hair Loss and Hair Genesis V

Posted on April 8, 2012 by Hair Loss Hair

Hair Genesis V in the News Again

Big news in the hair loss industry about Hair Loss and Hair Genesis V. New studies show big results.

I was reading a new finding in the Journal “Hair, Therapy & Transplantation” where scientists at The University of Albany, Center For Functional Genomics, were working collaboratively with Advanced Restoration Technologies (ART), DBA Hair Genesis V.

Take a read below to learn how new test results show great promise for hair loss.

Their latest findings from basic science experiments undertaken to test a novel, naturally derived hair loss treatment formula developed by ART. (http://www.omicsgroup.org/journals/htthome.php)

Chronic inflammation of the hair follicle is considered a contributing factor in the onset and progression of androgenetic alopecia (AGA) also known as pattern hair loss. Thus, investigators Sridar Chittur, Brian Parr & Geno Marcovici sought to test the study material’s ability to block certain markers of localized inflammation in scalp hair through the use of a well-validated molecular technique which mimics human hair follicle gene expression. Interestingly, the research team found that the test material reduced gene expression of three inflammatory cytokines thought to be linked to pattern hair loss.

Common hair loss affects over forty million American men and twenty million American women. The hair growth treatment industry constitutes a multi-billion dollar revenue stream annually.

In addition to anti-inflammatory properties, the test composition was formulated with a subset of botanically-derived, highly potent DHT inhibitors. DHT is the most well-described trigger of common pattern hair loss in women as well as men. By combining potent anti-inflammatory agents with powerful DHT inhibitors the test formula was designed to offer enhanced clinical efficacy over conventional monotherapy, such as Rogaine® (minoxidil 5%) or Propecia® (1 mg. finasteride).

Lead scientist for the work Sridar Chittur, Ph.D. has been at the forefront of molecular research authoring published works ranging from degenerative mitral valve disease (DMVD), to transcriptional changes associated with oxidative stress in the mitochondria. Co-author Brian Parr, Ph.D. brings a wealth of basic science expertise to the project with a number of peer-reviewed papers describing novel gene transcription and protein expression profiles in the Wnt and Frizzled pathways.

Study co-author Geno Marcovici, Ph.D. has been active in the hair loss field for almost two decades. His research efforts include the first published clinical trial successfully testing naturally derived 5 alpha reductase inhibitors in the setting of pattern hair loss. Explaining the importance of validating ART’s proprietary formulations Marcovici notes that “[a]side from Hair Genesis V, the naturally-derived hair treatments commercially available offer little or no objective evidence that they work. On the other hand, the drug-based treatments that do work come with potentially serious negative side effects. This tends to render Hair Genesis V a unique proposition in the category.”

Marcovici, also noted “one interesting observation described in this paper establishes the utility of our compositions in the clinical environment, including the potential deployment of Hair Genesis® as an adjunctive tool in autologous hair transplant surgery”.

Understanding HTT

Hair: Therapy & Transplantation (HTT), a broad based medical journal was founded on two tenets: To publish the most exciting research with respect to the subject of hair. And also to provide a rapid turn-around time for the review and publication of scientific discoveries that are highly relevant in this rapidly emerging field.

About The Center For Functional Genomics, SUNY

The Microarray Core Facility is a component of the University Of Albany Center for Functional Genomics and was established to provide the infrastructure to enable the development of major projects that utilize DNA microarrays for large-scale analysis of gene expression. The DNA Microarray Center currently employs two technologies for gene expression analysis: Affymetrix GeneChip arrays and custom-produced spotted cDNA microarrays. Projects developed through the DNA Microarray Center have made use of Affymetrix arrays from both eukaryotic as well as prokaryotic genomes. The Facility is also currently developing specialized custom printed arrays to examine gene expression in mouse tissues as part of a NIH funded Mutant Mouse Regional Resource Center.

About Advanced Restoration Technologies Inc., DBA Hair Genesis V

Combining scientific validation with the safety of natural ingredients, ART’s product line Hair Genesis V represents a unique therapeutic platform in the hair loss treatment category. Prior to focusing on basic science research, ART established a 10-year track record as a surgical center for IRB-monitored clinical investigation, testing new drugs as well as medical devices. ART-based published studies include those undertaken on behalf of Organogenesis, Canton, MA and Procyte Corporation, Kirkland, WA. It was from this research platform that Hair Genesis V was originally conceived and created. To view hair genesis products please visit Hair Genesis V.

Posted in Uncategorized | Tagged androgenetic alopecia, hair genesis, hair growth treatment, hair loss in women, minoxidil 5, pattern hair loss, scalp hair, university of albany | Leave a comment

Hairloss Within Females

Posted on March 16, 2012 by admin1

Regarding apolecia or thinning hair in women it can be seen in every age group and can be caused by many different factors.

There are several viable treatment options for the most common hair loss disorders affecting patients of either gender. In this article I will narrow the focus to hair loss experienced by women.

As a man, I know how debilitating hair loss can be. However, I cannot begin to imagine what it must be like to be a woman losing her hair. The emotional torment and sense of helplessness must be profoundly wrenching. Society is also less tolerant of female hair loss. A woman’s hair is described as her glory. It is a mark of pride, and also a source of attraction. Many, if not most, women invest a share of their identity in their hair. Thus, when hair loss strikes it can be devastating indeed.

The treatment of female pattern hair loss has historically be relegated to wigs as covering devices and/or lotions and potions which almost invariably failed to accomplish anything useful. In the past several decades the options have improved.

Today, there are basically three approaches to treating female hair loss. The first is covering/camouflage type devices. These include rather sophisticated hair pieces and scalp dyes to reduce the contrast between hair and scalp. The second option is surgical. Here, as with men, sections of hair bearing tissue are repositioned into areas of the scalp where hair has been lost. Unlike men, transplant surgery for women is often less than viable. This is because the area of hair loss in a woman may extend into the back of the scalp where thick hair is otherwise available for men suffering from pattern hair loss.

The third option involves medicinal treatment. The pharmaceutical based options indicated for use by women include spironalactone, hormone therapy and minoxidil.

Spironolactone, brand name Aldactone, is in a class of drugs called potassium-sparing diuretics (often called water pills). Spironolactone is typically used to reduce fluid in your body without causing the loss of potassium. It is also used to treat potassium deficiency, high blood pressure (hypertension), swelling (edema), and a hormonal disorder called hyperaldosteronism.

Spironolactone acts as an anti-androgen in two ways. First, it slows down the production of androgens in the adrenal glands and ovaries. Second, it blocks the action of androgens in part by preventing dihydrotestosterone (DHT) from binding to its androgenetic receptor.

Estrogen and progesterone pills and creams may be an effective treatment for women with androgenetic alopecia who are going through menopause or whose estrogen and/or progesterone are lacking for other reasons.

Some women have shown a positive response to the use of topical minoxidil. Results from a recent clinical study of women ages 18 to 45 years with mild to moderate degrees of hair loss report that after using minoxidil for eight months, only 19% of users had modest regrowth and 40% had minimal regrowth. However, negative side effects are also rather common. These include burning or irritation of the eyes, itching, redness or irritation in the treated scalp, as well as unwanted hair growth elsewhere on the body. Users should stop treatment and seek medical attention right away if they experience the severe side effects: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dizziness; fainting; fast heartbeat; sudden, unexplained weight gain; swollen hands or feet. Product labeling recommendations suggest that women only use the 2% concentration of minoxidil, not 5%, because the FDA has not approved use of the higher concentration in women.

An exciting area of research suggests that non-drug based compositions may offer greater efficacy in women than drug-based therapy – with the added benefit of being free from negative side effect. One is cautioned to limit the use of such compositions to those which have undergone empirically-tested and peer-review validated scientific research.

In our next installment we will address naturally-based substances that offer promise against pattern hair loss

As well you may want to take a look at another article called hair loss treatment for women.

Guest Author: Dr. Geno Marcovici – Hair Genesis V

Posted in Uncategorized | Tagged female hair loss, hair loss, hair loss in women, hair thinning, minoxidil, pattern hair loss, thick hair, thinning hair in women | Leave a comment

DO I NEED BOTH ORAL & TOPICAL HAIR LOSS TREATMENT?

Posted on March 11, 2012 by Hair Loss Hair

Oral and Topical Treatment For Hair Loss

Do you need to use both an oral & topical hair loss treatment.

So there you are at a dinner party, or out on a date, or simply washing your hands in the restroom when you glance at a mirror. Funny, didn’t I have a bit more hair last time I looked?

That gnawing sensation in the pit of your stomach is telling you something. Something you don’t want to hear or think about. Can it be true? Are you losing your hair? Anxiety gives way to panic which yields to depression. And in the fullness of time, when you’re ready to deal with the problem, you begin to think about choices.

Definitely no wigs. You’re not a wig wearing kind of person.

Transplant surgery? Makes you shudder to think of someone popping plugs into your scalp. No. Definitely not ready for that either. So that leaves….what?

Okay, how about drugs. Rogaine, that’s supposed to work fairly well. But what about side effects? Propecia, that one also has some pretty nasty side effects too.

There are naturally-based choices. But which of these to try? And should you go with an oral supplement or a topical treatment applied directly to the scalp? Too many choices. Too much mumbo jumbo pseudo-science gibberish. If only there was a quick and easy way to distill it all down so that the right decision could be made on the front end, and not after months and years and thousands of dollars are wasted on stuff that was more hype than reality.

Where to begin? Who can you trust? What should you do? All good questions. And there are good answers too.

Now days the internet can be your best friend. You should start by reading what science has learned about pattern hair loss in the past twenty years. You’ll soon realize that three factors conspire to create the problem, age, genetics, and circulating hormones. Can’t do much about the first two. But we’re starting to get a handle on the circulating hormones part. Second, who can you trust. Start with your primary care provider.

He or she is in the best position to offer you sound sensible advice. Third, what should you do. Here, your actions should be taken only after developing a clear understanding of the pros and cons of each treatment choice available.

Hair Loss Treatments

Perhaps Hair Genesis V is a good option for you. Perhaps not. You’ll want to compare our treatment methodology to everything else you see on the internet and learn about elsewhere. With the remainder of this post, I’d like to focus on one aspect of Hair Genesis V that makes us a little different from some of the other choices.

Almost since the inception of the product line, Hair Genesis V has been based on a combination of oral and focal treatment. This means that we go at the problem systemically through oral ingestion which eventually ends up in the bloodstream as well as locally by delivering active therapy to the scalp. Why do we do it this way?

As it happens, the skin is one of the few organ systems that is amenable to local and systemic treatment. This is why when you have a skin infection or rash your physician may often prescribe oral antibiotics and local steroid creams. Because you can treat the problem from both angles. When we realize that hair is merely an ectodermal appendage of the skin we can grasp why the same paradigm applies to hair pathology, e.g. common pattern hair loss.

It was with this recognition that very early in the development of Hair Genesis V.

It was with this recognition that very early in the development of Hair Genesis V we began to formulate compositions that could be efficiently delivered locally to the scalp and also systemically through the oral route. There is an inherent synergy in utilizing this strategy that is borne out by published research and almost twenty years of clinical experience.

Buy Hair Genesis V HERE

This paradigm constitues one key facet of differentiating Hair Genesis V from other choices. In follow up articles we will touch on several others. we began to formulate compositions that could be efficiently delivered locally to the scalp and also systemically through the oral route. There is an inherent synergy in utilizing this strategy that is borne out by published research and almost twenty years of clinical experience.

This paradigm constitues one key facet of differentiating Hair Genesis® from other choices. In follow up articles we will touch on several others.

Posted in Uncategorized | Tagged hair genesis, hair genesis v, hair loss treatment, hormones, oral supplement, pattern hair loss, Propecia, rogaine, topical treatment | Leave a comment

Vitamins and Minerals For Hair

Posted on March 9, 2012 by admin1

Vitamins for hair

Within the particular struggle to drop excess fat, usually we all neglect the every single day usage associated with nutritional supplements, as were cutting down on our calorie consumption.

The hair follicles need specif vitamins to fight hair loss and at the same time can help your body restore regular health as well. This may end up being a certain diet, that includes hair loss pills.

To stay young looking there are mainly 14 vitamins of which 6 are associated with helping you lose weight or body excess fat at the same time as growing hair. These particular vitamins are A, B, D, E, as well as Biotin, horestail (for women) and (Saw Palmetto for Men). Others include, thiamine, riboflavin, niacin, pantothenic acid, B12, folic acid, as well as pyridoxine.

Vitamin D and A are found in milk which are also critical for your bones. Vitamin A, can also be found in celery. Vitamin C, found in fruits assists your body with healing and Vitamin b complex, found in leafy green vegetables aids the body with the creation of proteins and vitality.

It’s not always easy to find Vitamin D in regular diets but all you need is a little sunshine, this will help. Also, Detoxing vitamins such as vitamin D and beta carotene help the body stay younger. If you do not have thinning hair or hair loss then a multi-vitamin will work great for you.

Although a multi-vitamin doesn’t contain specif hair loss vitamins they can help to keep the body healthy and younger looking.

Posted in Uncategorized | Tagged minerals, vitamins, vitamins and minerals | Leave a comment

Your Guide to How to Make Botanical Shampoo

Posted on March 7, 2012 by admin1

There is a stunning array both of botanical shampoos and their claims, to aid you in sorting out the claims here is a bit of information about botanical shampoos for you.

For starters, Most nice Botanical shampoo uses a base of castile soap. Castile soap is made from olive oil Most castile soaps out there use a blend of palm oil, olive oil, almond oil or coconut oil.

Almond oil and jojoba are added because not only do they nourish and moisten the scalp, they also provide a wonderful consistency to the shampoo. Jojoba wax (its actually a wax although its often called an oil) can be used to treat both damaged and dry hair, and almond is great for drying out oily hair.

Most commercial Botanical shampoos tend to include rosemary. not only because of its relatively low price but also because rosemary extractives encourages hair to grow longer and stronger by stimulating hair foliciles, It is widely believed that rosemary slows down premature hair loss and graying of the hair as well as being beneficial for Dandruff and dry scalps. Other common oils used to promote growth and add fragrance to shampoo are basil and peppermint.

One of the more useful infusions in botanical shampoo is ginger, Ginger helps to promote healthier hair that grows faster and is more resilient because it stimulates circulation to the scalp.

Lavender calms, reduces inflammation, cleanses, soothes and has slight drying properties. Lavender is also used to encourage growth.

There are a few different infusions that can help enhance your hairs natural color, for instance

brunettes benefit from rosemary, henna, and black tea infusions, while marigold, chamomile, or green tea can bring radiance back to blonde hair, Redheads enjoy a more brilliant full red color by utilizing infusions of Marshmallow leaves, Ginger, orange pekoe tea or hibiscus.

choosing the correct botanical shampoo for you can be difficult, definitely take the your hair type into consideration, then find or make the right botanical shampoo to fit your needs.

For example if you have thinning hair, the best shampoo for your thinning hair most likely would be a blend of rosemary, ginger and something to match your hair color. or for example if you have dry hair, you might use a blend of jojoba and rosemary with an herb to match your hair color as well.

Posted in Uncategorized | Tagged botanical shampoo | Comments Off

Hair Loss Product Comparison – Get The Facts

Posted on March 4, 2012 by Hair Loss Hair

Hair Loss Product Comparison

When looking at hair loss product comparisons you will see many bias ratings from those selling hair loss products. Just type in the words ‘hair loss product comparison‘ into any search engine and you’ll end up with pages and pages of search results that seem to offer the comparisons you’re looking for. Until that is, you actually click through to find that most bring you to a page or two containing lots of words and charts, but very little objective fact.

When a person is searching for information about a subject as important as choosing the right hair loss treatment, it only seems logical that they’re hoping to find objective data comparing apples to apples. Unfortunately, the hair loss treatment category is presently littered with the detritus of marketing materials designed less to provide an informative service than to separate the consumer from their cash.

One of the most common tactics is to post a comparison chart that purports to contrast a number of hair treatment products, but skews the facts so that the deck ends up being stacked heavily in favor of the product they’re actually trying to sell. Even more deceptively, a number of product brands have taken to publishing websites that look like objective third party comparison pages. Only close scrutiny brings to light the fact that the seemingly objective comparison page was actually created and funded by the product line that invariably wins the comparison. Aside from the fact that such ploys insult the intelligence of the consumer, they also do a grave disservice to the very people they purport to help.

A person seeking hair loss treatment comparison information wants to know — objectively — what actually makes one product formulation superior to another. Since most hair treatment product lines seem reluctant to provide this kind of information, one may reasonably conclude that very few hair loss product brands possess objective third party evidence that they offer genuine efficacy and safety.

Lab Testing Hair Loss Products

There are only a very few companies that have spent the required time needed to develop and test hair loss products. Hair Genesis V is the only company to have spent almost twenty years subjecting their formulations to a grueling but scientifically valid process of critical research and development. They have also presented their formulas for analysis and testing by third-party entities and then put the data before the peer-reviewed medical community. So for real hair loss product comparisons you need to be looking at trusted sources.

Hair Genesis V is unique in the non-drug hair loss treatment category by supporting product claims with proven scientific data and will show up at the top of any at hair loss product comparisons.

Posted in Uncategorized | Tagged hair genesis, hair genesis v, hair loss products, hair loss treatment, hairgenesis, provillus | Leave a comment

An Aging Hair Loss Understanding

Posted on January 18, 2012 by Hair Loss Hair

Aging Hair Loss

Aging hair loss is a common concern and we can help you understand it better.

Did you know that one of the most prolific areas of research these days is on aging and aging hair loss. From quality of life, to the onset of diseases associated with age, a key goal is to stack the deck in favor of healthful longevity. As a visible sign of advancing years, few physical changes are more obvious than progressive hair loss. Even for individuals who have escaped early-onset androgenetic alopecia, the later years take their toll and you will see aging hair loss.

Buy Hair Genesis HERE

Aging Hair Loss Basics

It is rare for people of either gender to reach seventy years of age with a full, intact dense head of hair because of aging hair loss. Senescent alopecia appears to follow a somewhat different etiological path than common androgen-based pattern hair loss. Instead of bitemporal recession and the progressive balding of the crown, a general loss of density occurs throughout the scalp. Hair aging comprises accumulated damage to the structures producing the hair shaft and involution of the hair follicle.

An intriguing clue into senescent alopecia may be found in a distantly related disorder, alopecia areata (AA). In AA, it is typical for pigmented hair to be targeted for attack, but hypo-pigmented (grey) hair is often spared. What does this tell us? Experimental evidence supports the hypothesis that oxidative stress plays a role in skin and hair aging. So, reagents that may blunt reactive oxygen species could hold promise in addressing senescent aging hair loss.

Additionally, the scalp is also subject to intrinsic or physiologic aging and extrinsic aging caused by external factors. Intrinsic factors are related to individual genetic and epigenetic mechanisms with population-based variation. Here, disease phenotypes include familial premature graying and, of course, androgenetic alopecia. Extrinsic factors include ultraviolet radiation and smoking. The cumulative result of extrinsic factors is a negative change in the efficient maintenance of hair cycle dynamics. Essentially, the hairs stop growing as robustly, regularly and efficiently as before.

A Cure For Aging Hair Loss

Almost daily, the news channels report substantive breakthroughs in advancing human health. New drugs, new approaches using molecular tools such as stem cells, and other 21st Century techniques herald an apparently endless stream of medical miracles. But what about garden variety common pattern or aging hair loss? It’s creeping into the future fast. So where’s the cure?

To begin, it is important to recognize the limitations researchers face in sorting out the pieces of the pattern hair loss puzzle. First limitation, no animal model. Unlike numerous diseases, ranging from cardiovascular disease to diabetes to Alzheimer’s, there simply is no animal model for common pattern hair loss.

Some of the most important breakthroughs in human disease have occurred as a result of work undertaken on animal models. This is not going to happen in pattern hair loss for reasons just noted. Second limitation, aging hair loss is a complex trait disorder. This means that there are numerous genes and other factors (biochemistry, age, circulating hormones, environment, etc.) that contribute to phenotype. It’s not just one thing that causes pattern hair loss.

For precisely this reason, in our lab we have moved away from focusing on DHT/5-alpha reductase. Newly published research by our group and collaborators at University of Albany show that inflammation plays a meaningful role in the onset and progression of pattern hair loss. Other factors will be important and we are working to understand what those may be.

Third limitation, many natural substances are largely undiscovered. Most drugs cause side effects. Fortunately, naturally-derived substances are less likely to cause this problem. However, we are still very early in the process of discovering the potential benefits which may be found in naturally-sourced molecules. This is one very important part of what we do to create better therapies and treatments. Still, while safe and effective treatments constitute the best of what we’re able to accomplish today, the future of aging hair loss research centers around finding an actual “cure”.

Posted in Uncategorized | Tagged androgenetic alopecia, Balding, epigenetic mechanisms, grey hair, hair cycle, pattern hair loss, progressive hair loss | Leave a comment

TOP 10 CELEBRITY BAD HAIR DAYS

Posted on January 5, 2012 by Hair Loss Hair

Here are some celebrity bad hair day pictures for you to enjoy. Yes! Celebrities are people too just like you and me and too can have bad hair days.

#10 Vice President Joe Biden

Here Mr. Biden explains the nuances of our delicate relationship with Russia. Or, he could just be blurting out another stream of random nonsense. Sometimes it’s kinda hard to tell.

#9 Donald Trump

The Donald waves to an adoring crowd with a bit of a windy hair look..

#8 Don King

No excuses. The man has crazy hair. Probably cause he’s more than just a little bonkers himself. A bit different than his normal bad hair look. Whoops did I just say that?

#8 Gwen Stefani

Oh, hey Gwen… still hot of course you Malibu Barbie. She wants her plastic hair back.

#7 Mel Gibson

Here, Mel affects the crazy sheriff character in the Insane Clown Posse group. What? There isn’t a character like that in the group is there? Where’s your cane and top hat?

#6 Cyndi Lauper

Girls just wanna have fun? Not with hair like that they don’t. Think she probably paid big bucks for that look when she could have just woke up with it.

#5 Brendan Frazier

Would someone please tell this guy about Hair Genesis!!!

#4 Larry King

Here’s living proof that you can indeed cross pollinate a person with an ear of corn.

#3 Mickey Rourke (as Elmer Fudd)

Be vewy vewy quiet. I’m hunting a waskawy wabbit! hhaaaaaaa..

#2 Russel Brand

Scissors and comb? Did someone here order a scissors and comb?

#1 Courtney Love

Here’s a fun fact. Did you know that thorazine and valium mixed together makes for a truly scrumptious milkshake?

Posted in Uncategorized | Tagged bad hair, bad hair days, celebrities, celebrity hair, crazy hair, hair genesis | 1 Comment

Hair Loss Hair